in vitro evaluation of the effect of dibutyl phthalate

In vitro evaluation of the effect of dibutyl phthalate on …

Dibutyl phthalate, a known endocrine disruptor, is a commonly used plasticizer that influences the glucose homeostasis. The present study elucidates the effects of dibutyl phthalate (1 and 5 mmol/L) on electrogenic sodium-linked glucose transport in the isolated rabbit ileum with ‘Ussing chamber.’,In vitro evaluation of the effect of dibutyl phthalate on … ,In vitro evaluation of the effect of dibutyl phthalate on electrogenic sodium-linked glucose transport in isolated rabbit ileum Khalid Abdul Majeed a, Muhammad Shahbaz Yousaf , Hafsa Zanebb …,In vitro evaluation of the effect of dibutyl phthalate on … ,ABSTRACT Dibutyl phthalate, a known endocrine disruptor, is a commonly used plasticizer that influences the glucose homeostasis. The present study elucidates the effects of dibutyl phthalate (1 and 5 mmol/L) on electrogenic sodium-linked glucose transport in the isolated rabbit ileum with ‘Ussing chamber.’ Serosal addition of dibutyl phthalate has no effect on glucose-based electrogenic …

In vitro evaluation of the effect of dibutyl phthalate on …

Request PDF | In vitro evaluation of the effect of dibutyl phthalate on electrogenic sodium linked glucose transport in isolated rabbit ileum | Dibutyl phthalate, a known endocrine disruptor, is a …,(PDF) In vitro evaluation of the effect of dibutyl … ,The absorption of glucose is electrogenic in the small intestinal epithelium. The major route for the transport of dietary glucose from intestinal lumen into enterocytes is the Na,In vitro evaluation of the effect of dibutyl phthalate on … ,Dibutyl phthalate, a known endocrine disruptor, is a commonly used plasticizer that influences the glucose homeostasis. The present study elucidates the effects of dibutyl phthalate (1 and 5mmol/L) on electrogenic sodium-linked glucose transport in the isolated rabbit ileum with Ussing chamber.'

Effects of in vitro exposure to dibutyl phthalate, mono …

Dibutyl phthalate (DBP) is present in consumer products and the coating of some oral medications. Acetyl tributyl citrate (ATBC) has been proposed as an alternative to DBP because DBP causes endocrine disruption in animal models.,Effects of in vitro exposure to dibutyl phthalate, mono … ,Effect of dibutyl phthalate, mono-butyl phthalate, and acetyl tributyl citrate on the growth of mouse antral follicles. Our first objective was to establish the dose–response relationship between exposure to each chemical and in vitro follicular growth.,The plasticizer dibutyl phthalate (DBP) potentiates … ,Recent studies suggest that phthalates may have a role in the development of allergic diseases, probably due to an adjuvant effect. The present study aimed to investigate the possible adjuvant effect of dibutyl phthalate (DBP) in two in vitro models of contact-allergen induced cell activation, namely the NCTC 2544 IL-18 assay and the THP-1 activation assay.

In vitro evaluation of the effect of dibutyl phthalate on …

Article “In vitro evaluation of the effect of dibutyl phthalate on electrogenic sodium-linked glucose transport in isolated rabbit ileum” Detailed information of the J-GLOBAL is a service based on the concept of Linking, Expanding, and Sparking, linking science and …,Effects of in vitro exposure to dibutyl phthalate, mono … ,Effect of dibutyl phthalate, mono-butyl phthalate, and acetyl tributyl citrate on the number of growing antral follicles. The transition from the early antral follicle to the preovulatory stage occurs quite rapidly and is mainly driven by the proliferation of granulosa cells .,Effects of in vitro exposure to dibutyl phthalate, mono … ,Effect of dibutyl phthalate, mono-butyl phthalate, and acetyl tributyl citrate on the growth of mouse antral follicles. Our first objective was to establish the dose–response relationship between exposure to each chemical and in vitro follicular growth.

Effects of dibutyl phthalate and di(2-ethylhexyl …

The aim of this article is to assess the effect of phthalates on the activities of CYP2C9 and CYP2C19 in vitro. In this study, recombinant CYP2C9*1 and CYP2C19*1 microsomes were used to investigate the effects of phthalates and their metabolites on corresponding enzyme activities in vitro.,In vitro genotoxicity of dibutyl phthalate on A549 lung … ,While in vitro studies are often based on submerged exposures, this study aimed to expose A549 alveolar epithelial cells at the air–liquid interface (ALI) to unravel the genotoxic and oxidative stress-inducing potential of dibutyl phthalate (DBP) with concentrations relevant at occupational settings.,Effects of dibutyl phthalate and di(2-ethylhexyl … ,The aim of this article is to assess the effect of phthalates on the activities of CYP2C9 and CYP2C19 in vitro. In this study, recombinant CYP2C9*1 and CYP2C19*1 microsomes were used to investigate the effects of phthalates and their metabolites on corresponding enzyme activities in vitro.

Dibutyl Phthalate – EPA

Dibutyl phthalate was detected in some drinking water supplies at levels ranging from 0.1 to 5 ppb. (1) Assessing Personal Exposure Tests are available that can detect dibutyl phthalate in blood and body tissues, and the major breakdown products of dibutyl phthalate can be measured in urine.,Effects of dibutyl phthalate and di(2-ethylhexyl) phthalate … ,The results showed dibutyl phthalate (DBP) significantly inhibited CYP2C9*1 with an activity inhibition rate of 67.3% and half-maximal inhibitory concentration (IC50) of 29.63 μmol L –1, but its metabolite monobutyl phthalate (MBP) had no significant effect.,Dibutyl Phthalate Inhibits the Effects of Follicle-Stimulating … ,Dibutyl phthalate (DBP) is used worldwide in solvents and plasticizers. The cytotoxicity and potential tumorigenic effect of DBP have been reported.

Effects of in vitro exposure to dibutyl phthalate, mono …

Effect of dibutyl phthalate, mono-butyl phthalate, and acetyl tributyl citrate on the growth of mouse antral follicles. Our first objective was to establish the dose–response relationship between exposure to each chemical and in vitro follicular growth.,Effects of in vitro exposure to dibutyl phthalate, mono … ,Dibutyl phthalate (DBP) is present in consumer products and the coating of some oral medications. Acetyl tributyl citrate (ATBC) has been proposed as an alternative to DBP because DBP causes endocrine disruption in animal models.,Mode of action and human relevance evaluation of Dibutyl … ,Mode of action and human relevance evaluation of Dibutyl Phthalate (DBP)-induced male reproductive system toxicity. Xabier Arzuaga.

Final Scope of the Risk Evaluation for Dibutyl Phthalate …

Final Scope of the Risk Evaluation for Dibutyl Phthalate (1,2-Benzenedicarboxylic acid, 1,2-dibutyl ester) CASRN 84-74-2 August 2020 . 2 …,Dibutyl Phthalate June 2008 – Industrial Chemicals ,This review of dibutyl phthalate (DBP) is a health hazard assessment only. For this assessment, two key reviews on DBP prepared by the European Chemicals Bureau and the US Centre for the Evaluation of Risks to Human Reproduction were consulted.,Dibutyl phthalate promotes juvenile Sertoli cell … ,Dibutyl phthalate (DBP) is a widely used plasticizer that has a negative effect on the development and function of male reproductive organs in humans and laboratory animals [1, 2].As DBP binds to the matrix by non-covalent bond, it easily leaches into the environment and then migrates into the food [].The toxicological effects of DBP are complex and diverse.

Dibutyl phthalate | Plasticizer | MedChemExpress

Dibutyl phthalate is a commonly used plasticizer commonly found in some food packaging materials, personal care products, and the coating of oral medications [1]. May cause toxicity and adverse neurobehavioral effects [2] [3] .,Dibutyl Phthalate Inhibits the Effects of Follicle-Stimulating … ,Dibutyl phthalate (DBP) is used worldwide in solvents and plasticizers. The cytotoxicity and potential tumorigenic effect of DBP have been reported.,Dibutyl phthalate; CASRN 84-74-2 ,1.25% dibutyl phthalate for a period of 1 year. One-half of all rats receiving the highest dibutyl phthalate concentration died during the first week of exposure.

[PDF] Effects of in vitro exposure to dibutyl phthalate …

Abstract Dibutyl phthalate (DBP) is present in consumer products and the coating of some oralmedications. Acetyl tributyl citrate (ATBC) has been proposed as an alternative to DBP because DBP causes endocrine disruption in animal models.,In vitro evaluation of the effect of dibutyl phthalate on … ,In vitro evaluation of the effect of dibutyl phthalate on electrogenic sodium-linked glucose transport in isolated rabbit ileum. Khalid Abdul Majeed, Muhammad Shahbaz Yousaf, Hafsa Zaneb, Imtiaz Rabbani, Zia Ur Rehman, Habib Rehman; Toxicological and Environmental Chemistry, November 2017, Taylor & Francis; DOI: 10.1080/02772248.2017.1393540,In vitro evaluation of the effect of dibutyl phthalate on … ,Article “In vitro evaluation of the effect of dibutyl phthalate on electrogenic sodium-linked glucose transport in isolated rabbit ileum” Detailed information of the J-GLOBAL is a service based on the concept of Linking, Expanding, and Sparking, linking science and …

Effects of in vitro exposure to dibutyl phthalate, mono …

Dibutyl phthalate (DBP) is present in consumer products and the coating of some oralmedications. Acetyl tributyl citrate (ATBC) has been proposed as an alternative to DBP because DBP causes endocrine disruption in animal models.,Effects of in vitro exposure to dibutyl phthalate, mono … ,Effect of dibutyl phthalate, mono-butyl phthalate, and acetyl tributyl citrate on the growth of mouse antral follicles. Our first objective was to establish the dose–response relationship between exposure to each chemical and in vitro follicular growth.,[PDF] Dibutyl Phthalate Inhibits the Effects of Follicle … ,ABSTRACT Dibutyl phthalate (DBP) is used worldwide in solvents and plasticizers. The cytotoxicity and potential tumorigenic effect of DBP have been reported.

Dibutyl phthalate promotes juvenile Sertoli cell …

Dibutyl phthalate (DBP) is a widely used plasticizer that has a negative effect on the development and function of male reproductive organs in humans and laboratory animals [1, 2].As DBP binds to the matrix by non-covalent bond, it easily leaches into the environment and then migrates into the food [].The toxicological effects of DBP are complex and diverse.,Effects of dibutyl phthalate and di(2-ethylhexyl) phthalate … ,The results showed dibutyl phthalate (DBP) significantly inhibited CYP2C9*1 with an activity inhibition rate of 67.3% and half-maximal inhibitory concentration (IC50) of 29.63 μmol L –1, but its metabolite monobutyl phthalate (MBP) had no significant effect.,Dibutyl Phthalate Inhibits the Effects of Follicle-Stimulating … ,Dibutyl phthalate (DBP) is used worldwide in solvents and plasticizers. The cytotoxicity and potential tumorigenic effect of DBP have been reported.